Pub. Date : 2014
PMID : 24132698
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dexamethasone in the presence of desipramine enhances MAPK/ERK1/2 signaling possibly via its interference with beta-arrestin. | Desipramine | mitogen-activated protein kinase 3 | Homo sapiens |
| 2 | We suggest that such an interaction in the presence of DMI can enhance MAPK/ERK1/2 signaling, a key player in neural plasticity and neurogenesis processes, which is impaired in MDD, while stimulated by antidepressants. | Desipramine | mitogen-activated protein kinase 3 | Homo sapiens |