Title : Involvement of a di-leucine motif in targeting of ABCC1 to the basolateral plasma membrane of polarized epithelial cells.

Pub. Date : 2013 Nov 8

PMID : 24129190






3 Functional Relationships(s)
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1 Involvement of a di-leucine motif in targeting of ABCC1 to the basolateral plasma membrane of polarized epithelial cells. di-leucine ATP binding cassette subfamily C member 1 Homo sapiens
2 Comparison of the CLD1 amino acid sequences from ABCC1 to ABCC2 revealed that ABCC1 possesses a characteristic sequence, E(295)EVEALI(301), which is comprised of a cluster of acidic glutamate residues followed by a di-leucine motif. di-leucine ATP binding cassette subfamily C member 1 Homo sapiens
3 Therefore, a di-leucine motif within the CLD1 is a basolateral targeting determinant of ABCC1. di-leucine ATP binding cassette subfamily C member 1 Homo sapiens