Pub. Date : 2014 Apr
PMID : 24118918
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vitro assessment of 36 CYP2C9 allelic isoforms found in the Chinese population on the metabolism of glimepiride. | glimepiride | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | This study provided the most comprehensive data on the enzymatic activities of all reported CYP2C9 variants in the Chinese population with regard to the commonly used antidiabetic drug, glimepiride. | glimepiride | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 3 | Our results indicate that most of the tested rare alleles significantly decrease the catalytic activity of CYP2C9 variants towards glimepiride hydroxylation in vitro. | glimepiride | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |