Title : Pyrroloquinoline quinone inhibits oxygen/glucose deprivation-induced apoptosis by activating the PI3K/AKT pathway in cardiomyocytes.

Pub. Date : 2014 Jan

PMID : 24114661






4 Functional Relationships(s)
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1 Pyrroloquinoline quinone inhibits oxygen/glucose deprivation-induced apoptosis by activating the PI3K/AKT pathway in cardiomyocytes. PQQ Cofactor AKT serine/threonine kinase 1 Rattus norvegicus
2 Western blotting was used to examine the effect of PQQ on the phosphatidylinositol 3-kinase (PI3K)/Akt pathway in the H9C2 cells. PQQ Cofactor AKT serine/threonine kinase 1 Rattus norvegicus
3 Western blot analysis showed that PQQ partially reversed the decrease in Akt phosphorylation that was caused by OGD (p < 0.05). PQQ Cofactor AKT serine/threonine kinase 1 Rattus norvegicus
4 The protective effect of PQQ may be related to its effects on the PI3K/Akt pathway. PQQ Cofactor AKT serine/threonine kinase 1 Rattus norvegicus