Title : Simvastatin ameliorates liver fibrosis via mediating nitric oxide synthase in rats with non-alcoholic steatohepatitis-related liver fibrosis.

Pub. Date : 2013

PMID : 24098525






2 Functional Relationships(s)
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1 Compared with model rats in 24(th) week group, rats in simvastatin group had less expressions of iNOS, alpha-SMA, and Collagen I and more expressions of eNOS. Simvastatin nitric oxide synthase 2 Rattus norvegicus
2 CONCLUSIONS: Simvastatin improves the prognosis of NASH-related fibrosis by increasing the expression of eNOS, decreasing the expression of iNOS, and inhibiting the activation of HSC. Simvastatin nitric oxide synthase 2 Rattus norvegicus