Pub. Date : 2014 Apr
PMID : 24092407
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | GPIAS showed that rats with long-term administration of salicylate were experiencing tinnitus, and the mRNA and protein expression levels of TNF-alpha and NR2A were up-regulated in chronic treatment groups, and they returned to baseline 14 days after cessation of treatment. | Salicylates | glutamate ionotropic receptor NMDA type subunit 2A | Rattus norvegicus |
2 | These data revealed that chronic salicylate administration markedly, but reversibly, induces tinnitus possibly via augmentation of the expression of TNF-alpha and NR2A and cause changes in synaptic ultrastructure in the CN. | Salicylates | glutamate ionotropic receptor NMDA type subunit 2A | Rattus norvegicus |