Title : Specific binding of modified ZD6474 (Vandetanib) monomer and its dimer with VEGF receptor-2.

Pub. Date : 2013 Nov 20

PMID : 24089699






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Vandetanib, also known as ZD6474, is an orally bioavailable small molecule tyrosine kinase inhibitor of multiple growth factors that is an antagonist of the vascular endothelial growth factor receptor-2 (VEGFR-2). vandetanib kinase insert domain receptor Homo sapiens
2 Vandetanib, also known as ZD6474, is an orally bioavailable small molecule tyrosine kinase inhibitor of multiple growth factors that is an antagonist of the vascular endothelial growth factor receptor-2 (VEGFR-2). vandetanib kinase insert domain receptor Homo sapiens
3 Vandetanib, also known as ZD6474, is an orally bioavailable small molecule tyrosine kinase inhibitor of multiple growth factors that is an antagonist of the vascular endothelial growth factor receptor-2 (VEGFR-2). vandetanib kinase insert domain receptor Homo sapiens
4 Vandetanib, also known as ZD6474, is an orally bioavailable small molecule tyrosine kinase inhibitor of multiple growth factors that is an antagonist of the vascular endothelial growth factor receptor-2 (VEGFR-2). vandetanib kinase insert domain receptor Homo sapiens
5 ZD6474 dimer demonstrated improved uptake in HUVECs and other VEGFR expressing cells over ZD6474 monomer in vitro. vandetanib kinase insert domain receptor Homo sapiens