Title : Circumvention of resistance to photodynamic therapy in doxorubicin-resistant sarcoma by photochemical internalization of gelonin.

Pub. Date : 2013 Dec

PMID : 24076428






1 Functional Relationships(s)
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1 A DOX-induced increased expression of the reactive oxygen species (ROS)-scavenging proteins glutathione peroxidase (GPx) 1 and GPx4 in MES-SA/Dx5 cells was indicated as the mechanism of resistance to PDT in line with the reduction in PDT-generated ROS observed in this cell line. Doxorubicin glutathione peroxidase 1 Homo sapiens