Title : Serotonin 2B receptor (5-HT2B R) signals through prostacyclin and PPAR-ß/δ in osteoblasts.

Pub. Date : 2013

PMID : 24069449

1 Functional Relationships(s)
Compound Name
Protein Name
1 We conclude that the absence of 5-HT2B receptors leads to the overproduction of prostacyclin, inducing reduced osteoblast differentiation due to PPAR-ss/delta -dependent target regulation and defective cell-cell adhesion and matrix mineralization. Epoprostenol peroxisome proliferator activator receptor delta Mus musculus