Title : Chronic insulin exposure does not cause insulin resistance but is associated with chemo-resistance in colon cancer cells.

Pub. Date : 2014 Feb

PMID : 24068609






1 Functional Relationships(s)
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1 In CIE-treated cells, there was reduced IR expression, incomplete IRS-1 adaptation, lack of signalling pathway attenuation and contra-adaptive increases in IRS-1 tyrosine phosphorylation in several cell types. Tyrosine insulin receptor substrate 1 Homo sapiens