Title : Increased extracellular glutamate in the nucleus accumbens promotes excessive ethanol drinking in ethanol dependent mice.

Pub. Date : 2014 Feb

PMID : 24067300






1 Functional Relationships(s)
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1 In contrast, reducing glutamatergic transmission in the NAc via bilateral injections of the metabotropic glutamate receptor-2/3 agonist LY379268 reduced drinking in dependent (EtOH) mice to nondependent (CTL) levels, whereas having a more modest effect in decreasing ethanol consumption in CTL mice. LY 379268 glutamate receptor, metabotropic 2 Mus musculus