Protein Name glutamate receptor, metabotropic 2
Organism Mus musculus
Gene ID 108068
Gene Symbol

Grm2

UniProt Q14BI2 (GRM2_MOUSE)
Relationships Total Number of functionally related compound(s) : 52
Total Number of Articles : 78
Description

glutamate receptor, metabotropic 2

Gene Summary

Enables calcium channel regulator activity and group II metabotropic glutamate receptor activity. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within gene expression; intracellular glutamate homeostasis; and long-term synaptic depression. Located in neuron projection. Is active in glutamatergic synapse and postsynaptic membrane. Is expressed in brain; cerebellum internal granule cell layer; and telencephalon. Orthologous to human GRM2 (glutamate metabotropic receptor 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • metabotropic glutamate receptor 2
  • G protein-coupled receptor, family C, group 1, member B
  • 4930441L02Rik
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Properties