Title : The role of multidrug resistance-1 (MDR1) variants in response to fexofenadine among Jordanians.

Pub. Date : 2013 Nov

PMID : 24040855






5 Functional Relationships(s)
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1 The role of multidrug resistance-1 (MDR1) variants in response to fexofenadine among Jordanians. fexofenadine ATP binding cassette subfamily B member 1 Homo sapiens
2 The role of multidrug resistance-1 (MDR1) variants in response to fexofenadine among Jordanians. fexofenadine ATP binding cassette subfamily B member 1 Homo sapiens
3 The P-gp has wide substrate specificity for multiple medications, including the antiallergic drug fexofenadine. fexofenadine ATP binding cassette subfamily B member 1 Homo sapiens
4 In this study, we investigated the possible association between three common MDR1 gene polymorphisms (G2677T, C3435T, and C1236T), and the anti-allergic effect of fexofenadine among Jordanians. fexofenadine ATP binding cassette subfamily B member 1 Homo sapiens
5 CONCLUSIONS: The MDR1 gene polymorphism C1236T was associated with the anti-allergic effect of fexofenadine among male Jordanians. fexofenadine ATP binding cassette subfamily B member 1 Homo sapiens