Title : Impact of CYP3A5 genetic polymorphisms on the pharmacokinetics and short-term remission in patients with ulcerative colitis treated with tacrolimus.

Pub. Date : 2014 Jan

PMID : 24033383






1 Functional Relationships(s)
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1 BACKGROUND AND AIM: The pharmacokinetics of tacrolimus (Tac) differ among individuals, and genetic polymorphisms of cytochrome P-450 (CYP) 3A4, CYP3A5, and ABCB1 are thought to be involved. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens