Title : Inhibition of mTOR signalling potentiates the effects of trichostatin A in human gastric cancer cell lines by promoting histone acetylation.

Pub. Date : 2014 Jan

PMID : 24030871






1 Functional Relationships(s)
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1 RAPA markedly inhibited cell proliferation, induced G1 cell cycle arrest, and reduced phosphorylation of p70 S6 protein kinase (p70S6K) and 4E-BP1 in GC cells, particularly when used in combination with LY294002 or TSA. trichostatin A ribosomal protein S6 kinase B1 Homo sapiens