Title : Hypotonic shock modulates Na(+) current via a Cl(-) and Ca(2+)/calmodulin dependent mechanism in alveolar epithelial cells.

Pub. Date : 2013

PMID : 24019969






2 Functional Relationships(s)
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1 A 20% bilateral hypotonic shock induced an immediate, but transient 52% rise in total transepithelial current and a 67% increase in the amiloride-sensitive current mediated by ENaC. Amiloride sodium channel epithelial 1 subunit gamma Rattus norvegicus
2 Amiloride pre-treatment decreased the current rise after hypotonic shock, showing that ENaC current is involved in this response. Amiloride sodium channel epithelial 1 subunit gamma Rattus norvegicus