CPRiL

Protein Name	sodium channel epithelial 1 subunit gamma
Organism	Rattus norvegicus
Gene ID	24768
Gene Symbol	Scnn1g
UniProt	P37091 (SCNNG_RAT)
Relationships	Total Number of functionally related compound(s) : 137 Total Number of Articles : 213
Description	sodium channel epithelial 1 subunit gamma
Gene Summary	Enables WW domain binding activity and ligand-gated sodium channel activity. Contributes to sodium ion transmembrane transporter activity. Involved in several processes, including intracellular sodium ion homeostasis; sodium ion import across plasma membrane; and wound healing, spreading of epidermal cells. Located in apical plasma membrane and cell surface. Human ortholog(s) of this gene implicated in Liddle syndrome; bronchiectasis 3; and pseudohypoaldosteronism. Orthologous to human SCNN1G (sodium channel epithelial 1 subunit gamma). [provided by Alliance of Genome Resources, Jul 2025]
synonyms	epithelial sodium channel subunit gamma SCNEG Sodium channel, nonvoltage-gated 1, gamma (epithelial) amiloride sensitive sodium channel gamma1 subunit amiloride-sensitive sodium channel subunit gamma epithelial Na(+) channel subunit gamma epithelial sodium channel gamma subunit gamma-ENaC gamma-NaCH nonvoltage-gated sodium channel 1 subunit gamma pithelial Na(+) channel subunit gamma sodium channel epithelial 1 gamma subunit sodium channel, non-voltage-gated 1, gamma subunit sodium channel, nonvoltage-gated, type I, gamma ENaC Click to show/hide the synonyms
Properties