Pub. Date : 2013 Nov 15
PMID : 24014677
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The nonselective COX inhibitor ketoprofen (2 mg/kg sc) given throughout the ANG-II infusion period attenuated HTN development in rats on 2% NaCl diet, but not in rats on 0.4% NaCl diet. | Ketoprofen | angiotensinogen | Rattus norvegicus |
| 2 | Ketoprofen-treated rats showed a smaller fall in arterial pressure in response to ganglion blockade during ANG-II infusion than did nontreated controls. | Ketoprofen | angiotensinogen | Rattus norvegicus |
| 3 | In additional experiments, ketoprofen-treated rats exhibited smaller increases in plasma norepinephrine levels and whole body norepinephrine spillover than we previously reported in ANG II-salt HTN. | Ketoprofen | angiotensinogen | Rattus norvegicus |