Title : The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma.

Pub. Date : 2014 Feb

PMID : 24013721






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 ZEB1 expression in MCL cells depends on Wnt, being downregulated by beta-catenin knockdown or blocking of Wnt signaling by salinomycin. salinomycin zinc finger E-box binding homeobox 1 Mus musculus
2 Downregulation of ZEB1 by salinomycin increases the sensitivity of MCL cells to the cytotoxic effect of doxorubicin, cytarabine and gemcitabine. salinomycin zinc finger E-box binding homeobox 1 Mus musculus