Pub. Date : 2013 Aug
PMID : 23991582
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OBJECTIVE: To investigate the influence of celecoxib, cycloxygenase-2 (COX-2) selective inhibitor, upon the proliferation of KB/VCR cells, and analyze the effect of celecoxib on the expression of P-glycoprotein (P-gp). | Celecoxib | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | OBJECTIVE: To investigate the influence of celecoxib, cycloxygenase-2 (COX-2) selective inhibitor, upon the proliferation of KB/VCR cells, and analyze the effect of celecoxib on the expression of P-glycoprotein (P-gp). | Celecoxib | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | The expression of P-gp in Celecoxib + VCR group and Celecoxib group were markedly lower, compared with those in VCR group and Celecoxib + VCR + PGE2 group (P < 0.01). | Celecoxib | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | The expression of P-gp in Celecoxib + VCR group and Celecoxib group were markedly lower, compared with those in VCR group and Celecoxib + VCR + PGE2 group (P < 0.01). | Celecoxib | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | The expression of P-gp in Celecoxib + VCR group and Celecoxib group were markedly lower, compared with those in VCR group and Celecoxib + VCR + PGE2 group (P < 0.01). | Celecoxib | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 6 | The mechanism probably correlates with the downregulation of celecoxib on the expression of P-gp and the increase of apoptosis. | Celecoxib | ATP binding cassette subfamily B member 1 | Homo sapiens |