Title : Design, synthesis, biological evaluation and docking study of 5-oxo-4,5-dihydropyrano[3,2-c]chromene derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.

Pub. Date : 2013 Oct

PMID : 23988409






2 Functional Relationships(s)
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1 A series of fused coumarins namely 5-oxo-4,5-dihydropyrano[3,2-c]chromenes linked to N-benzylpyridinium scaffold were synthesized and evaluated as acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitors. 5-oxo-4,5-dihydropyrano[3,2-c]chromenes acetylcholinesterase (Cartwright blood group) Homo sapiens
2 A series of fused coumarins namely 5-oxo-4,5-dihydropyrano[3,2-c]chromenes linked to N-benzylpyridinium scaffold were synthesized and evaluated as acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitors. 5-oxo-4,5-dihydropyrano[3,2-c]chromenes acetylcholinesterase (Cartwright blood group) Homo sapiens