Title : Rotenone directly induces BV2 cell activation via the p38 MAPK pathway.

Pub. Date : 2013

PMID : 23977201






2 Functional Relationships(s)
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1 In the present study, we found that rotenone, a mitochondrial complex I inhibitor, could directly activate microglia via the nuclear factor kappa B (NF-kappaB) signaling pathway, thereby inducing significantly increased expression of inflammatory cytokines. Rotenone nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 In the present study, we found that rotenone, a mitochondrial complex I inhibitor, could directly activate microglia via the nuclear factor kappa B (NF-kappaB) signaling pathway, thereby inducing significantly increased expression of inflammatory cytokines. Rotenone nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus