Title : Effect of CYP3A4*22, POR*28, and PPARA rs4253728 on sirolimus in vitro metabolism and trough concentrations in kidney transplant recipients.

Pub. Date : 2013 Dec

PMID : 23974086






1 Functional Relationships(s)
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1 RESULTS: In vitro, the CYP3A4*22 allele resulted in approximately 20% lower metabolic rates of SRL (P = 0.0411). Sirolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens