Pub. Date : 2013 Dec
PMID : 23973313
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NMDA receptors are ligand-gated ion channels that assemble into tetrameric receptor complexes composed of glycine-binding GluN1 and GluN3 subunits (GluN3A-B) and glutamate-binding GluN2 subunits (GluN2A-D). | Glycine | glutamate ionotropic receptor NMDA type subunit 1 | Homo sapiens |
| 2 | NMDA receptors can assemble as GluN1/N2 receptors and as GluN3-containing NMDA receptors, which are either glutamate/glycine-activated triheteromeric GluN1/N2/N3 receptors or glycine-activated diheteromeric GluN1/N3 receptors. | Glycine | glutamate ionotropic receptor NMDA type subunit 1 | Homo sapiens |
| 3 | NMDA receptors can assemble as GluN1/N2 receptors and as GluN3-containing NMDA receptors, which are either glutamate/glycine-activated triheteromeric GluN1/N2/N3 receptors or glycine-activated diheteromeric GluN1/N3 receptors. | Glycine | glutamate ionotropic receptor NMDA type subunit 1 | Homo sapiens |
| 4 | The glycine-binding GluN1 and GluN3 subunits display strikingly different pharmacological selectivity profiles. | Glycine | glutamate ionotropic receptor NMDA type subunit 1 | Homo sapiens |