Title : The Tudor domain of the PHD finger protein 1 is a dual reader of lysine trimethylation at lysine 36 of histone H3 and lysine 27 of histone variant H3t.

Pub. Date : 2014 Apr 17

PMID : 23954330






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sub-nuclear localization studies of full-length PHF1 in human HEK293 cells revealed that it co-localizes with K27me3, but not with K36me3, and that this co-localization depends on the trimethyllysine binding pocket indicating that K27me3 is an in vivo target for the PHF1 Tudor domain. trimethyllysine PHD finger protein 1 Homo sapiens