Title : The metabolic modulator trimetazidine triggers autophagy and counteracts stress-induced atrophy in skeletal muscle myotubes.

Pub. Date : 2013 Oct

PMID : 23953053






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In particular, we found that TMZ was able to activate the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin 2 pathway and to reduce the stress-induced transcriptional upregulation of atrogin-1, muscle ring finger protein 1, and myostatin, all of which are key molecules involved in muscle wasting. Trimetazidine F-box protein 32 Homo sapiens