Title : Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye.

Pub. Date : 2013

PMID : 23935957






1 Functional Relationships(s)
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1 Genetic inactivation of Atm in the central nervous system of Nbn-deficient mice led to reduced life span and increased DSBs, resulting in increased apoptosis during neural development. 1,2-di-(4-sulfamidophenyl)-4-butylpyrazolidine-3,5-dione ataxia telangiectasia mutated Mus musculus