Title : Pilot study assessing a seven-day continuous intrathecal topotecan infusion for recurrent or progressive leptomeningeal metastatic cancer.

Pub. Date : 2014 Jun

PMID : 23929729






2 Functional Relationships(s)
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1 CSF concentration of topotecan closed lactone ranged from 3.73 to 312 ng/mL (median = 131 ng/mL) and plasma topotecan closed lactone ranged from 0.44 to 1.78 ng/mL (median = 0.92 ng/mL). Topotecan colony stimulating factor 2 Homo sapiens
2 The median CSF topotecan concentration was greater than the median serum topotecan concentration by a 44-fold magnitude when samples were obtained at the same time point. Topotecan colony stimulating factor 2 Homo sapiens