Pub. Date : 2015 Jan
PMID : 23929704
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To further elucidate the detailed mechanism of MC-LR-induced cytoskeletal assembly, we focused on two cytoskeletal-related proteins, Tau and VASP. | cyanoginosin LR | vasodilator stimulated phosphoprotein | Homo sapiens |
| 2 | VASP was also hyperphosphorylated upon MC-LR exposure; however, its phosphorylation appeared to regulate its cellular localization rather than cytoskeletal dynamics, and its phosphorylation was unaffected by the PP2A activator. | cyanoginosin LR | vasodilator stimulated phosphoprotein | Homo sapiens |
| 3 | Tau hyperphosphorylation is likely an important factor leading to the cytoskeletal destabilization triggered by MC-LR and the role of VASP alteration upon MC-LR exposure needs to be studied further. | cyanoginosin LR | vasodilator stimulated phosphoprotein | Homo sapiens |
| 4 | To our knowledge, the finding that Tau is implicated in cytoskeletal destabilization in MC-LR-treated hepatocytes and MC-LR-induced VASP"s alteration has not been reported previously. | cyanoginosin LR | vasodilator stimulated phosphoprotein | Homo sapiens |