Pub. Date : 2013 Nov
PMID : 23927864
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The PPARgamma agonist rosiglitazone prevents neuronal loss and attenuates development of spontaneous recurrent seizures through BDNF/TrkB signaling following pilocarpine-induced status epilepticus. | Rosiglitazone | brain derived neurotrophic factor | Homo sapiens |
| 2 | In the present study, the PPARgamma agonist rosiglitazone inhibited increases in BDNF and TrkB after status epilepticus (SE), and also prevented hippocampal neuronal loss. | Rosiglitazone | brain derived neurotrophic factor | Homo sapiens |
| 3 | Thus, our data provide evidence that rosiglitazone exerts neuroprotective and antiepileptic effects involve BDNF/TrkB signaling. | Rosiglitazone | brain derived neurotrophic factor | Homo sapiens |