Pub. Date : 1975 Aug
PMID : 239224
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Analgesic doses of morphine and viminol R2 increase the turnover rate of dopamine (DA) in rat striatum but fail to increase the striatal concentration of adenosine 3",5"-monophosphate (cAMP) or the affinity of tyrosine hydroxylase (TH) for the pteridine cofactor. | Morphine | tyrosine hydroxylase | Rattus norvegicus |
| 2 | Analgesic doses of morphine and viminol R2 increase the turnover rate of dopamine (DA) in rat striatum but fail to increase the striatal concentration of adenosine 3",5"-monophosphate (cAMP) or the affinity of tyrosine hydroxylase (TH) for the pteridine cofactor. | Morphine | tyrosine hydroxylase | Rattus norvegicus |
| 3 | Similarly to morphine, haloperidol enhances the turnover rate of striatal DA, but unlike morphine it increases the affinity of TH for the pteridine cofactor and blocks the in vitro activation of striatal adenylacte cyclase by DA. | Morphine | tyrosine hydroxylase | Rattus norvegicus |