Pub. Date : 2014 May
PMID : 23922235
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Are curcuminoids effective C-reactive protein-lowering agents in clinical practice? | curcuminoids | C-reactive protein | Homo sapiens |
2 | Curcuminoids have been suggested to lower circulating levels of CRP, but clinical findings have not been consistent. | curcuminoids | C-reactive protein | Homo sapiens |
3 | OBJECTIVES: To pool the published results of clinical trials on the impact of supplementation with curcuminoids on circulating levels of CRP. | curcuminoids | C-reactive protein | Homo sapiens |
4 | METHODS: PubMed/MEDLINE and SCOPUS databases were searched for clinical trials reporting circulating CRP changes in individuals receiving curcuminoids. | curcuminoids | C-reactive protein | Homo sapiens |
5 | Compared with placebo, supplementation with curcuminoids was associated with a significant reduction in circulating CRP levels (weighed mean difference: -6.44 mg/L; 95% CI: -10.77 - -2.11; p = 0.004). | curcuminoids | C-reactive protein | Homo sapiens |
6 | CONCLUSIONS: Supplementation with curcuminoids may reduce circulating CRP levels. | curcuminoids | C-reactive protein | Homo sapiens |