Title : Are curcuminoids effective C-reactive protein-lowering agents in clinical practice? Evidence from a meta-analysis.

Pub. Date : 2014 May

PMID : 23922235






6 Functional Relationships(s)
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1 Are curcuminoids effective C-reactive protein-lowering agents in clinical practice? curcuminoids C-reactive protein Homo sapiens
2 Curcuminoids have been suggested to lower circulating levels of CRP, but clinical findings have not been consistent. curcuminoids C-reactive protein Homo sapiens
3 OBJECTIVES: To pool the published results of clinical trials on the impact of supplementation with curcuminoids on circulating levels of CRP. curcuminoids C-reactive protein Homo sapiens
4 METHODS: PubMed/MEDLINE and SCOPUS databases were searched for clinical trials reporting circulating CRP changes in individuals receiving curcuminoids. curcuminoids C-reactive protein Homo sapiens
5 Compared with placebo, supplementation with curcuminoids was associated with a significant reduction in circulating CRP levels (weighed mean difference: -6.44 mg/L; 95% CI: -10.77 - -2.11; p = 0.004). curcuminoids C-reactive protein Homo sapiens
6 CONCLUSIONS: Supplementation with curcuminoids may reduce circulating CRP levels. curcuminoids C-reactive protein Homo sapiens