PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23922235-0 2014 Are curcuminoids effective C-reactive protein-lowering agents in clinical practice? curcuminoids 4-16 C-reactive protein Homo sapiens 27-45 23922235-5 2014 Curcuminoids have been suggested to lower circulating levels of CRP, but clinical findings have not been consistent. curcuminoids 0-12 C-reactive protein Homo sapiens 64-67 23922235-6 2014 OBJECTIVES: To pool the published results of clinical trials on the impact of supplementation with curcuminoids on circulating levels of CRP. curcuminoids 99-111 C-reactive protein Homo sapiens 137-140 23922235-7 2014 METHODS: PubMed/MEDLINE and SCOPUS databases were searched for clinical trials reporting circulating CRP changes in individuals receiving curcuminoids. curcuminoids 138-150 C-reactive protein Homo sapiens 101-104 23922235-12 2014 Compared with placebo, supplementation with curcuminoids was associated with a significant reduction in circulating CRP levels (weighed mean difference: -6.44 mg/L; 95% CI: -10.77 - -2.11; p = 0.004). curcuminoids 44-56 C-reactive protein Homo sapiens 116-119 23922235-14 2014 CONCLUSIONS: Supplementation with curcuminoids may reduce circulating CRP levels. curcuminoids 34-46 C-reactive protein Homo sapiens 70-73