Title : Direct inhibition and down-regulation by uremic plasma components of hepatic uptake transporter for SN-38, an active metabolite of irinotecan, in humans.

Pub. Date : 2014 Jan

PMID : 23921491






1 Functional Relationships(s)
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1 Kinetic analyses for OATP-mediated transport revealed that the uptake of SN-38 by OATP1B1 was the highest, followed by OATP1B3. Irinotecan solute carrier organic anion transporter family member 1B3 Homo sapiens