Title : MiR-125b, miR-100 and miR-99a co-regulate vincristine resistance in childhood acute lymphoblastic leukemia.

Pub. Date : 2013 Oct

PMID : 23915977






1 Functional Relationships(s)
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1 Cellular viability of ETV6-RUNX1-positive Reh cells significantly increased in presence of 9 ng/mL vincristine upon co-expression of miR-125b/miR-99a (91 +- 4%), miR-125b/miR-100 (93 +- 5%) or miR-125b/miR-99a/miR-100 (82 +- 17%) compared with miR-125b-transduced cells (38 +- 13%, P<0.05). 125b RUNX family transcription factor 1 Homo sapiens