Title : Influence of GSTM1 and NAT2 genotypes on the relationship between personal exposure to PAH and biomarkers of internal dose.

Pub. Date : 1998

PMID : 23899393






5 Functional Relationships(s)
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1 Influence of GSTM1 and NAT2 genotypes on the relationship between personal exposure to PAH and biomarkers of internal dose. Polycyclic Aromatic Hydrocarbons N-acetyltransferase 2 Homo sapiens
2 After stratifying by genetic polymorphism the correlation between personal PAH exposure and urinary PAH metabolites increased for individuals with NAT2 slow acetylators (r 0.58, p 0.001, n 29) and the combination of GSTM1 null and NAT2 slow acetylators (r 0.60, p 0.01, n 16). Polycyclic Aromatic Hydrocarbons N-acetyltransferase 2 Homo sapiens
3 After stratifying by genetic polymorphism the correlation between personal PAH exposure and urinary PAH metabolites increased for individuals with NAT2 slow acetylators (r 0.58, p 0.001, n 29) and the combination of GSTM1 null and NAT2 slow acetylators (r 0.60, p 0.01, n 16). Polycyclic Aromatic Hydrocarbons N-acetyltransferase 2 Homo sapiens
4 After stratifying by genetic polymorphism the correlation between personal PAH exposure and urinary PAH metabolites increased for individuals with NAT2 slow acetylators (r 0.58, p 0.001, n 29) and the combination of GSTM1 null and NAT2 slow acetylators (r 0.60, p 0.01, n 16). Polycyclic Aromatic Hydrocarbons N-acetyltransferase 2 Homo sapiens
5 After stratifying by genetic polymorphism the correlation between personal PAH exposure and urinary PAH metabolites increased for individuals with NAT2 slow acetylators (r 0.58, p 0.001, n 29) and the combination of GSTM1 null and NAT2 slow acetylators (r 0.60, p 0.01, n 16). Polycyclic Aromatic Hydrocarbons N-acetyltransferase 2 Homo sapiens