Title : Cellular impedance assays for predictive preclinical drug screening of kinase inhibitor cardiovascular toxicity.

Pub. Date : 2013 Oct

PMID : 23897988






1 Functional Relationships(s)
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Protein Name
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1 Microtubule-associated protein/microtubule affinity regulating kinase (MARK) inhibitors decrease blood pressure in dogs, whereas checkpoint kinase (Chk) inhibitors (AZD7762, SCH900776) exhibit dose-limiting CV toxicities in clinical trials. MK-8776 megakaryocyte-associated tyrosine kinase Homo sapiens