Title : Can intracellular signalling pathways predict developmental abnormalities?

Pub. Date : 1996

PMID : 23888922






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 On gestational day 14, acute administration of terbutaline to pregnant rats resulted in sixfold induction of c-fos mRNA within 1 h; the same increase was obtained when a membrane-permeable analogue of cAMP was given. Terbutaline Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 Treatment with dexamethasone on gestational days 11,12 and 13 produced the same increase in c-fos mRNA on gestational day 14 as had been seen with acute terbutaline or CAMP; no further increase could be obtained with acute CAMP treatment in the dexamethasone-pretreated animals. Terbutaline Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus