Title : Structural insights into central hypertension regulation by human aminopeptidase A.

Pub. Date : 2013 Aug 30

PMID : 23888046






1 Functional Relationships(s)
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1 In the central renin-angiotensin system, zinc-dependent aminopeptidase A (APA) up-regulates blood pressure by specifically cleaving the N-terminal aspartate, but not the adjacent arginine, from angiotensin II, a process facilitated by calcium. Aspartic Acid angiotensinogen Homo sapiens