Title : Central cholinergic activation of a vagus nerve-to-spleen circuit alleviates experimental colitis.

Pub. Date : 2014 Mar

PMID : 23881354






1 Functional Relationships(s)
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1 Central cholinergic activation induced by the acetylcholinesterase inhibitor galantamine or a muscarinic acetylcholine receptor agonist treatments resulted in reduced mucosal inflammation associated with decreased major histocompatibility complex II level and pro-inflammatory cytokine secretion by splenic CD11c+ cells mediated by alpha7nAChR signaling. Galantamine integrin subunit alpha X Homo sapiens