Title : ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells.

Pub. Date : 2013

PMID : 23874979






1 Functional Relationships(s)
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1 Relative to controls, U0126-treated cells showed constitutive decreases in phosphorylation through a T cell receptor stimulation time course on tyrosine residues found on upstream signaling proteins (CD3 chains, Lck, ZAP-70), as well as downstream signaling proteins (VAV1, PLCgamma1, Itk, NCK1). U 0126 phospholipase C gamma 1 Homo sapiens