Title : Nicotinic receptor partial agonists modulate alcohol deprivation effect in C57BL/6J mice.

Pub. Date : 2013 Sep

PMID : 23872372






4 Functional Relationships(s)
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1 Pre-clinical and clinical studies have shown that neuronal nicotinic acetylcholine receptor (nAChR) partial agonists such as cytisine and its derivative, varenicline, reduce alcohol (ethanol) consumption and seeking behavior. Ethanol cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Pre-clinical and clinical studies have shown that neuronal nicotinic acetylcholine receptor (nAChR) partial agonists such as cytisine and its derivative, varenicline, reduce alcohol (ethanol) consumption and seeking behavior. Ethanol cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
3 The results from this study indicate that nAChR partial agonists reduce the expression of ADE in mice and further suggest the involvement of nAChR mechanisms in ADE, a relapse-like ethanol drinking behavior. Ethanol cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
4 The results from this study indicate that nAChR partial agonists reduce the expression of ADE in mice and further suggest the involvement of nAChR mechanisms in ADE, a relapse-like ethanol drinking behavior. Ethanol cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus