Title : Long term alterations in synaptic physiology, expression of β2 nicotinic receptors and ERK1/2 signaling in the hippocampus of rats with prenatal nicotine exposure.

Pub. Date : 2013 Nov

PMID : 23871741






4 Functional Relationships(s)
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1 Long term alterations in synaptic physiology, expression of beta2 nicotinic receptors and ERK1/2 signaling in the hippocampus of rats with prenatal nicotine exposure. Nicotine mitogen activated protein kinase 3 Rattus norvegicus
2 Moreover, reduced levels of beta2 subunit containing nicotinic receptors and extracellular signal regulated kinase1/2 (ERK1/2) were observed in nicotine exposed rats. Nicotine mitogen activated protein kinase 3 Rattus norvegicus
3 Moreover, reduced levels of beta2 subunit containing nicotinic receptors and extracellular signal regulated kinase1/2 (ERK1/2) were observed in nicotine exposed rats. Nicotine mitogen activated protein kinase 3 Rattus norvegicus
4 These results suggest that long lasting alterations in excitatory synaptic physiology, AMPAR synaptic currents and ERK1/2 signaling may serve as the molecular mechanisms for cognitive deficits associated with prenatal nicotine exposure. Nicotine mitogen activated protein kinase 3 Rattus norvegicus