Title : Culturing primary rat inner medullary collecting duct cells.

Pub. Date : 2013 Jun 21

PMID : 23852264






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 This stimulates cellular signaling processes leading to changes in the phosphorylation of the water channel aquaporin-2 (AQP2). Water aquaporin 2 Rattus norvegicus
2 Protein kinase A phoshorylates AQP2 and thereby triggers the translocation of AQP2 from intracellular vesicles into the plasma membrane facilitating water reabsorption from primary urine. Water aquaporin 2 Rattus norvegicus
3 Protein kinase A phoshorylates AQP2 and thereby triggers the translocation of AQP2 from intracellular vesicles into the plasma membrane facilitating water reabsorption from primary urine. Water aquaporin 2 Rattus norvegicus
4 The cells are suitable for elucidating molecular mechanisms underlying the control of AQP2 and thus to discover novel drug targets for the treatment of diseases associated with dysregulation of AVP-mediated water reabsorption. Water aquaporin 2 Rattus norvegicus