Pub. Date : 2013 Jun 21
PMID : 23852264
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This stimulates cellular signaling processes leading to changes in the phosphorylation of the water channel aquaporin-2 (AQP2). | Water | aquaporin 2 | Rattus norvegicus |
2 | Protein kinase A phoshorylates AQP2 and thereby triggers the translocation of AQP2 from intracellular vesicles into the plasma membrane facilitating water reabsorption from primary urine. | Water | aquaporin 2 | Rattus norvegicus |
3 | Protein kinase A phoshorylates AQP2 and thereby triggers the translocation of AQP2 from intracellular vesicles into the plasma membrane facilitating water reabsorption from primary urine. | Water | aquaporin 2 | Rattus norvegicus |
4 | The cells are suitable for elucidating molecular mechanisms underlying the control of AQP2 and thus to discover novel drug targets for the treatment of diseases associated with dysregulation of AVP-mediated water reabsorption. | Water | aquaporin 2 | Rattus norvegicus |