Title : Association study of sorbitol dehydrogenase -888G>C polymorphism with type 2 diabetic retinopathy in Caucasian-Brazilians.

Pub. Date : 2013 Oct

PMID : 23850972






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Hyperglycemia increases glucose flux through the polyol pathway, in which aldose reductase converts glucose into intracellular sorbitol, which is subsequently converted to fructose by sorbitol dehydrogenase (SDH). Sorbitol sorbitol dehydrogenase Homo sapiens
2 Hyperglycemia increases glucose flux through the polyol pathway, in which aldose reductase converts glucose into intracellular sorbitol, which is subsequently converted to fructose by sorbitol dehydrogenase (SDH). Sorbitol sorbitol dehydrogenase Homo sapiens