Pub. Date : 2013 Sep
PMID : 23842742
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Herein, we report that nicotine, an unselective alpha7-nAChR agonist, protects from morphological and synaptic impairments induced by Abeta oligomers. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 2 | On the other hand, a cross-talk between alpha7-nAChR and the Wnt/beta-catenin signaling pathway was revealed by the following facts: (1) nicotine stabilizes beta-catenin, in a concentration-dependent manner; (2) nicotine prevents Abeta-induced loss of beta-catenin through the alpha7-nAChR; and (3) activation of canonical Wnt/beta-catenin signaling induces alpha7-nAChR expression. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 3 | On the other hand, a cross-talk between alpha7-nAChR and the Wnt/beta-catenin signaling pathway was revealed by the following facts: (1) nicotine stabilizes beta-catenin, in a concentration-dependent manner; (2) nicotine prevents Abeta-induced loss of beta-catenin through the alpha7-nAChR; and (3) activation of canonical Wnt/beta-catenin signaling induces alpha7-nAChR expression. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 4 | On the other hand, a cross-talk between alpha7-nAChR and the Wnt/beta-catenin signaling pathway was revealed by the following facts: (1) nicotine stabilizes beta-catenin, in a concentration-dependent manner; (2) nicotine prevents Abeta-induced loss of beta-catenin through the alpha7-nAChR; and (3) activation of canonical Wnt/beta-catenin signaling induces alpha7-nAChR expression. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 5 | On the other hand, a cross-talk between alpha7-nAChR and the Wnt/beta-catenin signaling pathway was revealed by the following facts: (1) nicotine stabilizes beta-catenin, in a concentration-dependent manner; (2) nicotine prevents Abeta-induced loss of beta-catenin through the alpha7-nAChR; and (3) activation of canonical Wnt/beta-catenin signaling induces alpha7-nAChR expression. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |