Title : Carbenoxolone blocks endotoxin-induced protein kinase R (PKR) activation and high mobility group box 1 (HMGB1) release.

Pub. Date : 2013 Jul 24

PMID : 23835906






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The pathogen- and damage-associated molecular patterns (for example, bacterial endotoxin and adenosine 5"-triphosphate [ATP]) activate the double-stranded RNA-activated protein kinase R (PKR) to trigger the inflammasome-dependent high mobility group box 1 (HMGB1) release. Adenosine Triphosphate high mobility group box 1 Homo sapiens
2 The pathogen- and damage-associated molecular patterns (for example, bacterial endotoxin and adenosine 5"-triphosphate [ATP]) activate the double-stranded RNA-activated protein kinase R (PKR) to trigger the inflammasome-dependent high mobility group box 1 (HMGB1) release. Adenosine Triphosphate high mobility group box 1 Homo sapiens
3 The pathogen- and damage-associated molecular patterns (for example, bacterial endotoxin and adenosine 5"-triphosphate [ATP]) activate the double-stranded RNA-activated protein kinase R (PKR) to trigger the inflammasome-dependent high mobility group box 1 (HMGB1) release. Adenosine Triphosphate high mobility group box 1 Homo sapiens
4 The pathogen- and damage-associated molecular patterns (for example, bacterial endotoxin and adenosine 5"-triphosphate [ATP]) activate the double-stranded RNA-activated protein kinase R (PKR) to trigger the inflammasome-dependent high mobility group box 1 (HMGB1) release. Adenosine Triphosphate high mobility group box 1 Homo sapiens