Title : Low-dose radiation-induced enhancement of thymic lymphomagenesis in Lck-Bax mice is dependent on LET and gender.

Pub. Date : 2013 Aug

PMID : 23819597






2 Functional Relationships(s)
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Protein Name
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1 The hypothesis that mitochondrial dysfunction and increased superoxide levels in thymocytes over expressing Bax (Lck-Bax1 and Lck-Bax38&1) contributes to lymphomagenesis after low-dose radiation was tested. Superoxides lymphocyte protein tyrosine kinase Mus musculus
2 Sirt3(-/-)/Lck-Bax38&1 mice demonstrated significant increases in thymocyte superoxide levels and acceleration of lymphomagenesis (P < 0.001). Superoxides lymphocyte protein tyrosine kinase Mus musculus