Pub. Date : 2013 Jun
PMID : 23815902
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Efficacy of dasatinib in treatment of imatinib-resistant BCR/ABL positive leukemia]. | Dasatinib | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |
| 2 | This study was aimed to evaluate the efficacy and safety of dasatinib in BCR/ABL positive leukemia patients with primary or secondary resistance to imatinib. | Dasatinib | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |
| 3 | The results showed that the median duration of dasatinib therapy was 8 (1-66) months in the 27 imatinib-resistant BCR/ABL positive leukemia cases, with a median follow-up of 54 (3-75) months. | Dasatinib | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |
| 4 | It is concluded that dasatinib is an effective drug in imatinib-resistant BCR/ABL positive leukemia patients, the better curative effect and better tolerance has been observed in patients who received dasatinib in stable disease. | Dasatinib | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |