Title : Nicotinic acetylcholine receptors containing the α6 subunit contribute to ethanol activation of ventral tegmental area dopaminergic neurons.

Pub. Date : 2013 Oct 15

PMID : 23811312






2 Functional Relationships(s)
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1 Recent evidence indicates that nicotinic acetylcholine receptors (nAChRs), ligand-gated cation channels activated by ACh and nicotine, may contribute to ethanol-mediated activation of VTA DAergic neurons although the nAChR subtype(s) involved has not been fully elucidated. Ethanol cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Ethanol-induced activity in WT slices was also reduced by pre-application of the alpha6 subtype-selective nAChR antagonist, alpha-conotoxin MII[E11A]. Ethanol cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus